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Article

Synergistic effect of apolipoprotein E polymorphisms and cigarette smoking on risk of ischemic stroke in young adults.

Stroke - 1 Feb 2004

Pezzini Alessandro, Grassi Mario, Del Zotto Elisabetta, Bazzoli Elena, Archetti Silvana, Assanelli Deodato, Akkawi Nabil Maalikjy, Albertini Alberto, Padovani Alessandro

Abstract excerpt

BACKGROUND AND PURPOSE: The effect of apolipoprotein E (APOE) polymorphisms on stroke risk may be influenced by the coexistence of modifiable predisposing conditions. We explored the interactions of APOE genotypes and conventional risk factors in a case-control study of young adults with cerebral infarct. METHODS: We analyzed 124 consecutive patients (age, 34.7+/-7.3 years) and 147 age- and sex-matched controls....

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Source

Identifiers

PMID: 14726545
DOI: 10.1161/01.STR.0000112973.00867.98

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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