Article
APOE epsilon4 and Alzheimer's disease: positive association in a Colombian clinical series and review of the Latin-American studies.
Arquivos de neuro-psiquiatria - 1 Mar 2001
Jacquier M, Arango D, Villareal E, Torres O, Serrano M L, Cruts M, Montañes P, Cano C, Rodriguez M N, Serneels S, Van Broeckhoven C
Abstract excerpt
OBJECTIVE: As the strength of the association between the APOE epsilon4 allele and Alzheimer's disease (AD) varies across ethnic groups, we studied if there was such an association in Colombian patients. METHOD: We performed apolipoprotein E (APOE) genotyping in a clinical sample of 83 unrelated AD patients, predominantly late-onset (>65 yrs) including familial ( n =30) and sporadic AD cases (n= 53) diagnosed...
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