Article
Apolipoprotein E epsilon4 and the risk of dementia with stroke. A population-based investigation.
JAMA - 12 Mar 1997
Slooter A J, Tang M X, van Duijn C M, Stern Y, Ott A, Bell K, Breteler M M, Van Broeckhoven C, Tatemichi T K, Tycko B, Hofman A, Mayeux R
Abstract excerpt
OBJECTIVE: To investigate the association between the apolipoprotein E (APOE) genotypes and dementia in patients with stroke, defined as either vascular dementia (VaD) or Alzheimer disease with cerebrovascular disease (AD with CVD). DESIGN AND SETTING: Population-based, case-control study from Ro...
Topics
- Aged
- Aged, 80 and over
- Alleles
- Analysis of Variance
- Apolipoproteins E
- Case-Control Studies
- Cerebrovascular Disorders
- Dementia
- Female
- Gene Frequency
- Genotype
- Humans
- Logistic Models
- Male
- Neuropsychological Tests