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Article

Dose dependent effect of APOE epsilon4 on behavioral symptoms in frontal lobe dementia.

Neurobiology of aging - 1 Feb 2006

Engelborghs Sebastiaan, Dermaut Bart, Mariën Peter, Symons Anoek, Vloeberghs Ellen, Maertens Karen, Somers Nore, Goeman Johan, Rademakers Rosa, Van den Broeck Marleen, Pickut Barbara, Cruts Marc, Van Broeckhoven Christine, De Deyn Peter P

Abstract excerpt

To determine whether apolipoprotein alleles (APOE) influence behavioral and psychological signs and symptoms of dementia (BPSD), we initiated a prospective, longitudinal study. Patients with Alzheimer's disease (AD) (N=186), frontotemporal dementia (FTD) (N=29), mixed dementia (MXD) (N=28), dementia with Lewy bodies (DLB) (N=11) and Parkinson's disease dementia (PDD) (N=7) were included. Blood was collected for...

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Source

Identifiers

PMID: 16399213
DOI: 10.1016/j.neurobiolaging.2005.02.005

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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