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Article

DJ-1 interacts with HIPK1 and affects H2O2-induced cell death.

Free radical research - 1 Feb 2006

Sekito Aya, Koide-Yoshida Shizuyo, Niki Takeshi, Taira Takahiro, Iguchi-Ariga Sanae M M, Ariga Hiroyoshi

Abstract excerpt

DJ-1 is a novel oncogene and causative gene for the familial form of Parkinson's disease (PD). DJ-1 has multiple functions, including anti-oxidative stress by eliminating reactive oxygen species (ROS) and transcriptional regulation as a coactivator, and loss of these functions are thought to trigger the onset of PD. The mechanism underlying the prevention of cell death by DJ-1 is, however, not clear. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16390825
DOI: 10.1080/10715760500456847

Genes

HIPK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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DJ-1 interacts with HIPK1 and affects H2O2-induced cell death.PMID 16390825Read ↗

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