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Article

DJ-1 modulates aggregation and pathogenesis in models of Huntington's disease.

Human molecular genetics - 1 Feb 2014

Sajjad Muhammad U, Green Edward W, Miller-Fleming Leonor, Hands Sarah, Herrera Federico, Campesan Susanna, Khoshnan Ali, Outeiro Tiago F, Giorgini Flaviano, Wyttenbach Andreas

Abstract excerpt

The oxidation-sensitive chaperone protein DJ-1 has been implicated in several human disorders including cancer and neurodegenerative diseases. During neurodegeneration associated with protein misfolding, such as that observed in Alzheimer's disease and Huntington's disease (HD), both oxidative st...

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Identifiers

PMID: 24070869
DOI: 10.1093/hmg/ddt466

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24070869-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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