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Article

Association analysis of the chromosome 4p-located G protein-coupled receptor 78 (GPR78) gene in bipolar affective disorder and schizophrenia.

Molecular psychiatry - 1 Apr 2006

Underwood S L, Christoforou A, Thomson P A, Wray N R, Tenesa A, Whittaker J, Adams R A, Le Hellard S, Morris S W, Blackwood D H R, Muir W J, Porteous D J, Evans K L

Abstract excerpt

The orphan G protein-coupled receptor 78 (GPR78) gene lies within a region of chromosome 4p where we have previously shown linkage to bipolar affective disorder (BPAD) in a large Scottish family. GPR78 was screened for single-nucleotide polymorphisms (SNPs) and a linkage disequilibrium map was constructed. Six tagging SNPs were selected and tested for association on a sample of 377 BPAD, 392 schizophrenia (SCZ)...

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PMID: 16389273
DOI: 10.1038/sj.mp.4001786

Genes

GPR78

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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