Article
Association analyses suggest GPR24 as a shared susceptibility gene for bipolar affective disorder and schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jul 2006
Severinsen J E, Als T D, Binderup H, Kruse T A, Wang A G, Vang M, Muir W J, Blackwood D H R, Mors O, Børglum A D
Abstract excerpt
Linkage analyses suggest that chromosome 22q12-13 may harbor a shared susceptibility locus for bipolar affective disorder (BPD) and schizophrenia (SZ). In a study of a sample from the Faeroe Islands we have previously reported association between both disorders and microsatellite markers in a 3.6 cM segment on 22q13. The present study investigated three candidate genes located in this segment: GPR24, ADSL, and...
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