Article
Refinement of chromosome 3p22.3 region and identification of a susceptibility gene for bipolar affective disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2013
Secolin Rodrigo, Banzato Claudio E M, Mella Lucas F B, Santos Marilza L, Dalgalarrondo Paulo, Lopes-Cendes Iscia
Abstract excerpt
Genome-wide association studies and meta-analysis, as well as our own previous family-based association results, have pointed to chromosome (ch) 3p22.3 and 3p21.1 as candidate regions to contain a susceptibility gene for bipolar affective disorder (BPAD). In the present study, we further refined the region of interest on ch 3p22.3. We genotyped 94 SNPs within the candidate region in 74 families and performed...
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