Article
Support for a bipolar affective disorder susceptibility locus on chromosome 12q24.3.
Psychiatric genetics - 1 Jun 2010
Buttenschøn Henriette Nørmølle, Buttenchøn Henriette Nørmølle, Foldager Leslie, Flint Tracey J, Olsen Inger Marie L, Deleuran Thomas, Nyegaard Mette, Hansen Mette M, Kallunki Pekka, Christensen Kenneth V, Blackwood Douglas H, Muir Walter J, Straarup Steen E, Als Thomas D, Nordentoft Merete, Børglum Anders D, Mors Ole
Abstract excerpt
OBJECTIVE: Linkage and association studies of bipolar affective disorder (BAD) point out chromosome 12q24 as a region of interest. METHODS: To investigate this region further, we conducted an association study of 22 DNA markers within a 1.14 Mb region in a Danish sample of 166 patients with BAD and 311 control individuals. Two-hundred and four Danish patients with schizophrenia were also included in the study....
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