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Article

Association of GPR50, an X-linked orphan G protein-coupled receptor, and affective disorder in an independent sample of the Scottish population.

Neuroscience letters - 21 May 2010

Macintyre Donald J, McGhee Kevin A, Maclean Alan W, Afzal Maryam, Briffa Katy, Henry Brian, Thomson Pippa A, Muir Walter J, Blackwood Douglas H R

Abstract excerpt

A recent report detected association between GPR50, an orphan G protein-coupled receptor, and bipolar disorder (BD) in the Scottish population [29]. We sought to replicate this study in a second sample from the same population, consisting of 338 patients with BD, 359 patients with major depressive disorder (MDD) and 913 control individuals. In addition, the effect of GPR50 genotype on clinical phenotype and...

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Source

Identifiers

PMID: 20371266
DOI: 10.1016/j.neulet.2010.03.072

Genes

GPR50

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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