Article
Haplotype analysis and a novel allele-sharing method refines a chromosome 4p locus linked to bipolar affective disorder.
Biological psychiatry - 15 Mar 2007
Le Hellard Stephanie, Lee Andrew J, Underwood Sarah, Thomson Pippa A, Morris Stewart W, Torrance Helen S, Anderson Susan M, Adams Richard R, Navarro Pau, Christoforou Andrea, Houlihan Lorna M, Detera-Wadleigh Sevilla, Owen Michael J, Asherson Philip, Muir Walter J, Blackwood Douglas H R, Wray Naomi R, Porteous David J, Evans Kathryn L
Abstract excerpt
BACKGROUND: Bipolar affective disorder (BPAD) and schizophrenia (SCZ) are common conditions. Their causes are unknown, but they include a substantial genetic component. Previously, we described significant linkage of BPAD to a chromosome 4p locus within a large pedigree (F22). Others subsequently...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
