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Article

Heat shock-independent induction of multidrug resistance by heat shock factor 1.

Molecular and cellular biology - 1 Jan 2006

Tchénio Thierry, Havard Marilyne, Martinez Luis A, Dautry François

Abstract excerpt

The screening of two different retroviral cDNA expression libraries to select genes that confer constitutive doxorubicin resistance has in both cases resulted in the isolation of the heat shock factor 1 (HSF1) transcription factor. We show that HSF1 induces a multidrug resistance phenotype that o...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
Share to Doxorubicin
Share to Drug Resistance, Multiple

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Library

Share to Genes, MDR

Share to Heat-Shock Response

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Share to RNA Processing, Post-Transcriptional

Source

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Identifiers

PMID: 16382149
DOI: 10.1128/MCB.26.2.580-591.2006
PMCID: PMC1346900

Genes

HSF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16382149-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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