Article
Non-oncogene addiction and the stress phenotype of cancer cells.
Cell - 21 Sept 2007
Solimini Nicole L, Luo Ji, Elledge Stephen J
Abstract excerpt
Heat-shock factor 1 (HSF1) is a transcription factor that is activated upon proteotoxic stress and coordinates induction of the heat-shock response. In this issue, Dai et al. (2007) show that HSF1 is a potent modifier of tumorigenesis and is required for tumor initiation and maintenance in a vari...
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