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Article

Modulation of tolerance by mutant heat shock transcription factors.

Cell stress & chaperones - 1 Mar 1999

Xia W, Vilaboa N, Martin J L, Mestril R, Guo Y, Voellmy R

Abstract excerpt

It ought to be possible to recruit normal cellular defenses to mitigate ischemia/reperfusion damage and to reduce toxicity of chemotherapeutic drugs. Stress-preconditioned cells acquire a tolerant state characterized by increased resistance to such insults. This state is widely believed to be mediated, partially, by heat shock proteins (Hsps). Indirect evidence suggests that stress-induced Hsp expression is...

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Identifiers

PMID: 10467104
DOI: 10.1006/csac.1998.0113
PMCID: PMC312913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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