Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Kinetics of cancer: a method to test hypotheses of genetic causation.

BMC cancer - 21 Dec 2005

Frank Steven A, Chen Peng-Chieh, Lipkin Steven M

Abstract excerpt

BACKGROUND: Mouse studies have recently compared the age-onset patterns of cancer between different genotypes. Genes associated with earlier onset are tentatively assigned a causal role in carcinogenesis. These standard analyses ignore the great amount of information about kinetics contained in age-onset curves. We present a method for analyzing kinetics that measures quantitatively the causal role of candidate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoma
Share to Age of Onset
Share to Algorithms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma

Share to Disease Progression

Share to DNA Repair

Share to Gastrointestinal Neoplasms

Share to Lymphoma

Source

Open in PubMed Open full text

Identifiers

PMID: 16371164
DOI: 10.1186/1471-2407-5-163
PMCID: PMC1352380

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Kinetics of cancer: a method to test hypotheses of genetic causation.PMID 16371164Read ↗

Age-specific acceleration of cancer.Semantic proximity Read ↗

Estimating the carcinogenesis timelines in early-onset versus late-onset cancers and changes across birth cohortsSemantic proximity Read ↗

Multi-organ Mapping of Cancer Risk.Semantic proximity Read ↗

Challenging the axiom: does the occurrence of oncogenic mutations truly limit cancer development with age?Semantic proximity Read ↗

Segregating DNA lesions point to high selective advantage of tumor initiating cellsSemantic proximity Read ↗

Long-Term Latency of Highly Mutated Cells in Normal Mouse Skin Is Reversed by Exposure to Tumor Promoters and Chronic Tissue Damage.Semantic proximity Read ↗

Age-specific incidence of cancer: Phases, transitions, and biological implicationsSemantic proximity Read ↗

A statistical model for the identification of genes governing the incidence of cancer with age.Semantic proximity Read ↗

MECHANISMS OF RADIATION CARCINOGENESIS: WHAT IS REALLY INDUCED?Semantic proximity Read ↗

Human-mouse comparison of the multistage nature of radiation carcinogenesis in a mathematical model.Semantic proximity Read ↗

Multistage carcinogenesis modeling and the initiation event.Semantic proximity Read ↗

Puzzles in modern biology. III.Two kinds of causality in age-related diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.