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Article

Increased synaptic microtubules and altered synapse development in Drosophila sec8 mutants.

BMC biology - 13 Dec 2005

Liebl Faith L W, Chen Kaiyun, Karr Julie, Sheng Qi, Featherstone David E

Abstract excerpt

BACKGROUND: Sec8 is highly expressed in mammalian nervous systems and has been proposed to play a role in several aspects of neural development and function, including neurite outgrowth, calcium-dependent neurotransmitter secretion, trafficking of ionotropic glutamate receptors and regulation of neuronal microtubule assembly. However, these models have never been tested in vivo. Nervous system development and...

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Identifiers

PMID: 16351720
DOI: 10.1186/1741-7007-3-27
PMCID: PMC1326216

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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