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Article

Drosophila alpha- and beta-spectrin mutations disrupt presynaptic neurotransmitter release.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Jun 2001

Featherstone D E, Davis W S, Dubreuil R R, Broadie K

Abstract excerpt

Spectrins are plasma membrane-associated cytoskeletal proteins implicated in several aspects of synaptic development and function, including presynaptic vesicle tethering and postsynaptic receptor aggregation. To test these hypotheses, we characterized Drosophila mutants lacking either alpha- or beta-spectrin. The Drosophila genome contains only one alpha-spectrin and one conventional beta-spectrin gene, making...

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Identifiers

PMID: 11404407
PMCID: PMC6762771

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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