Article
Thymidine analogue mutations in antiretroviral-naive HIV-1 patients on triple therapy including either zidovudine or stavudine.
The Journal of antimicrobial chemotherapy - 1 Jan 2004
Bocket Laurence, Yazdanpanah Yazdan, Ajana Faïza, Gerard Yann, Viget Nathalie, Goffard Anne, Alcaraz Isabelle, Wattré Pierre, Mouton Yves
Abstract excerpt
AIMS: The aims of this study were to: (i) determine the incidence of thymidine-associated mutations (TAMs) in an observational clinical cohort of naive HIV-1 patients who stopped first-line therapy including either zidovudine or stavudine; and (ii) assess the immunological and virological responses to subsequent second-line therapy in patients who switched from zidovudine to stavudine or conversely. PATIENTS AND...
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