Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Aclidinium inhibits human lung fibroblast to myofibroblast transition

28 Sept 2011

Abstract excerpt

BACKGROUND: Fibroblast to myofibroblast transition is believed to contribute to airway remodelling in lung diseases such as asthma and chronic obstructive pulmonary disease. This study examines the role of aclidinium, a new long-acting muscarinic antagonist, on human fibroblast to myofibroblast transition. METHODS: Human bronchial fibroblasts were stimulated with carbachol (10(-8) to 10(-5) M) or transforming...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma and respiratory diseases
Share to Phosphodiesterase function and regulation
Share to Receptor Mechanisms and Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21957094
DOI: 10.1136/thoraxjnl-2011-200376

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Aclidinium inhibits human lung fibroblast to myofibroblast transitionPMID 21957094Read ↗

Fibroblast-to-myofibroblast transition in bronchial asthmaSemantic proximity Read ↗

Bradykinin differentiates human lung fibroblasts to a myofibroblast phenotype via the B2 receptor.Semantic proximity Read ↗

[Fibroblasts and lung fibrosis].Semantic proximity Read ↗

Fibroblast-myofibroblast transition is differentially regulated by bronchial epithelial cells from asthmatic children.Semantic proximity Read ↗

Transforming Growth Factor-Beta Produced by Non-small Cell Lung Cancer Cells Contributes to Lung Fibroblast Contractile Phenotype.Semantic proximity Read ↗

MAPK pathway mediates muscarinic receptor-induced human lung fibroblast proliferationSemantic proximity Read ↗

Epithelial vs myofibroblast differentiation in immortal rat lung cell lines--modulating effects of bleomycin.Semantic proximity Read ↗

Inhibition of TGFb-induced Fibroblast to Myofibroblast Transition by Conditioned Medium from Human Rhinovirus-infected Airway Epithelial Cells is Mediated by Prostaglandin E2Semantic proximity Read ↗

Cysteinyl leukotrienes synergize with growth factors to induce proliferation of human bronchial fibroblastsSemantic proximity Read ↗

Human tenocytes are stimulated to proliferate by acetylcholine through an EGFR signalling pathway.Semantic proximity Read ↗

Selective restoration of calcium coupling to muscarinic M(3) receptors in contractile cultured airway myocytes.Semantic proximity Read ↗

Superoxide Anion Inhibits Intracellular Calcium Response in Porcine Airway Smooth Muscle CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.