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Article

Therapies for bleomycin induced lung fibrosis through regulation of TGF‐β1 induced collagen gene expression

23 Mar 2007

Abstract excerpt

This review describes normal and abnormal wound healing, the latter characterized by excessive fibrosis and scarring, which for lung can result in morbidity and sometimes mortality. The cells, the extracellular matrix (ECM) proteins, and the growth factors regulating the synthesis, degradation, and deposition of the ECM proteins will be discussed. Therapeutics with particular emphasis given to gene therapies and...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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PMID: 17387717
DOI: 10.1002/jcp.20972

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