Article
Beta1-adrenergic receptor polymorphisms and clinical efficacy of betaxolol hydrochloride in normal volunteers.
Ophthalmology - 1 Dec 2005
Schwartz Stephen G, Puckett Brian J, Allen Robert C, Castillo Ivan G, Leffler Christopher T
Abstract excerpt
OBJECTIVE: To evaluate the relationship between polymorphisms in the gene encoding the beta1-adrenergic receptor (beta1-AR) and clinical response to betaxolol hydrochloride 0.25% in a small pilot study of normal volunteers. DESIGN: Prospective nonrandomized comparative trial. PARTICIPANTS: Forty-eight consecutive normal volunteers who met all eligibility requirements for inclusion into this study. METHODS:...
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