Article
Beta 1-adrenergic receptor polymorphisms and antihypertensive response to metoprolol.
Clinical pharmacology and therapeutics - 1 Jul 2003
Johnson Julie A, Zineh Issam, Puckett Brian J, McGorray Susan P, Yarandi Hossein N, Pauly Daniel F
Abstract excerpt
OBJECTIVES: Marked interpatient variability exists in blood pressure response to beta-blocker monotherapy. We tested the hypothesis that 2 common polymorphisms in the gene for beta(1)-adrenergic receptor are associated with antihypertensive response to metoprolol in patients with uncomplicated hy...
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