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Article

Polymorphism of the beta-2 adrenoceptor and IOP lowering potency of topical timolol in healthy subjects.

Molecular vision - 23 Sept 2005

Fuchsjager-Mayrl Gabriele, Markovic Ognjen, Losert Doris, Lucas Trevor, Wachek Volker, Muller Markus, Schmetterer Leopold

Abstract excerpt

PURPOSE: Beta-2 adrenoceptor antagonists such as timolol have been used in the treatment of glaucoma for more than 30 years. Several functionally important polymorphisms for the beta-2 receptor have been described. In the present study we hypothesized that a relation between the intraocular pressure (IOP) lowering effect of timolol and beta-2 adrenoceptor polymorphisms may exist. METHODS: A total of 270 healthy...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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PMID: 16205624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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