Article
ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin ligase complexes.
FEBS letters - 19 Dec 2005
Kohroki Junya, Nishiyama Takehiro, Nakamura Takaaki, Masuho Yasuhiko
Abstract excerpt
The ankyrin repeat and SOCS box (ASB) family is composed of 18 proteins from ASB1 to ASB18 and belongs to the suppressor of cytokine signaling (SOCS) box protein superfamily. ASB2 was recently shown to interact with a certain Cul-Rbx module to form an E3 ubiquitin (Ub) ligase complex, but the functional composition of the ASB-containing E3 Ub ligase complexes remains to be characterized. Here, we show that ASB...
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