Article
The interleukin-6 gene -174G>C and -572G>C promoter polymorphisms are related to cerebral aneurysms.
Journal of neurology, neurosurgery, and psychiatry - 1 Aug 2006
Morgan L, Cooper J, Montgomery H, Kitchen N, Humphries S E
Abstract excerpt
BACKGROUND AND AIMS: An important part is played by inflammation in intracranial aneurysm formation. The hypothesis that there is an association of the proinflammatory cytokine interleukin-6 (IL-6) genotypes (-572G>C and -174G>C) with intracranial aneurysms was tested. METHODS: IL-6 genotypes were determined in 91 Caucasian patients with aneurysms and compared with 2720 healthy UK controls. RESULTS: For both...
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