Article
Single-nucleotide polymorphism-based population genetic analysis of Mycobacterium tuberculosis strains from 4 geographic sites.
The Journal of infectious diseases - 1 Jan 2006
Gutacker Michaela M, Mathema Barun, Soini Hanna, Shashkina Elena, Kreiswirth Barry N, Graviss Edward A, Musser James M
Abstract excerpt
We studied genetic relationships among 5069 Mycobacterium tuberculosis strains recovered from patients enrolled in 4 population-based studies in the United States and Europe, by analysis of 36 synonymous single-nucleotide polymorphisms (SNPs). All strains were assigned to 1 of 9 major genetic clu...
Topics
- Bacterial Typing Techniques
- DNA Transposable Elements
- Europe
- Humans
- Mycobacterium tuberculosis
- Oligonucleotides
- Phylogeny
- Polymorphism, Restriction Fragment Length
- Polymorphism, Single Nucleotide
- Tuberculosis, Pulmonary
- United States