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Article

Single-nucleotide polymorphism-based population genetic analysis of Mycobacterium tuberculosis strains from 4 geographic sites.

The Journal of infectious diseases - 1 Jan 2006

Gutacker Michaela M, Mathema Barun, Soini Hanna, Shashkina Elena, Kreiswirth Barry N, Graviss Edward A, Musser James M

Abstract excerpt

We studied genetic relationships among 5069 Mycobacterium tuberculosis strains recovered from patients enrolled in 4 population-based studies in the United States and Europe, by analysis of 36 synonymous single-nucleotide polymorphisms (SNPs). All strains were assigned to 1 of 9 major genetic clusters based on sSNP profile. The same 9 genetic clusters were revealed by analysis of 227 nonsynonymous SNPs, 121...

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PMID: 16323140
DOI: 10.1086/498574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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