Article
Genetic diversity and dynamic distribution of Mycobacterium tuberculosis isolates causing pulmonary and extrapulmonary tuberculosis in Thailand.
Journal of clinical microbiology - 1 Dec 2014
Srilohasin Prapaporn, Chaiprasert Angkana, Tokunaga Katsushi, Nishida Nao, Prammananan Therdsak, Smittipat Nat, Mahasirimongkol Surakameth, Chaiyasirinroje Boonchai, Yanai Hideki, Palittapongarnpim Prasit
Abstract excerpt
This study examined the genetic diversity and dynamicity of circulating Mycobacterium tuberculosis strains in Thailand using nearly neutral molecular markers. The single nucleotide polymorphism (SNP)-based genotypes of 1,414 culture-positive M. tuberculosis isolates from 1,282 pulmonary tuberculosis (PTB) and 132 extrapulmonary TB (EPTB) patients collected from 1995 to 2011 were characterized. Among the eight SNP...
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