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Article

Single nucleotide polymorphisms in Mycobacterium tuberculosis and the need for a curated database.

Tuberculosis (Edinburgh, Scotland) - 1 Jan 2013

Stucki David, Gagneux Sebastien

Abstract excerpt

Recent advances in DNA sequencing have led to the discovery of thousands of single nucleotide polymorphisms (SNPs) in clinical isolates of Mycobacterium tuberculosis complex (MTBC). This genetic variation has changed our understanding of the differences and phylogenetic relationships between strains. Many of these mutations can serve as phylogenetic markers for strain classification, while others cause drug...

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PMID: 23266261
DOI: 10.1016/j.tube.2012.11.002
PMCID: PMC3582841

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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