Article
A robust SNP barcode for typing Mycobacterium tuberculosis complex strains.
Nature communications - 1 Sept 2014
Coll Francesc, McNerney Ruth, Guerra-Assunção José Afonso, Glynn Judith R, Perdigão João, Viveiros Miguel, Portugal Isabel, Pain Arnab, Martin Nigel, Clark Taane G
Abstract excerpt
Strain-specific genomic diversity in the Mycobacterium tuberculosis complex (MTBC) is an important factor in pathogenesis that may affect virulence, transmissibility, host response and emergence of drug resistance. Several systems have been proposed to classify MTBC strains into distinct lineages and families. Here, we investigate single-nucleotide polymorphisms (SNPs) as robust (stable) markers of genetic...
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