Article
The use of genetic markers to determine risk for prostate cancer at prostate biopsy.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Dec 2005
Nam Robert K, Zhang William W, Jewett Michael A S, Trachtenberg John, Klotz Laurence H, Emami Marjan, Sugar Linda, Sweet Joan, Toi Ants, Narod Steven A
Abstract excerpt
PURPOSE: We examined a panel of 13 polymorphisms in 13 different genes to determine whether specific genotypes can help predict prostate cancer at the time of biopsy among men prescreened with prostate-specific antigen and digital rectal exam. EXPERIMENTAL DESIGN: We examined 2,088 consecutive men who were referred for prostate biopsy from 1997 to 2003. Thirteen genes were examined, including TNF308, GSTT1, KLK2,...
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