Article
Prostate cancer risk alleles significantly improve disease detection and are associated with aggressive features in patients with a "normal" prostate specific antigen and digital rectal examination.
The Prostate - 1 Mar 2011
Helfand Brian T, Kan Donghui, Modi Parth, Catalona William J
Abstract excerpt
BACKGROUND: Several reports suggest that a combination of risk alleles may be associated with prostate cancer (CaP) risk and tumor features. However, their ability to detect CaP and tumor characteristics in patients with a "normal" PSA (<4 ng/ml) and non-suspicious digital rectal examination (DRE) remains to be determined. METHODS: We examined 203 men of European ancestry with clinical stage T1c CaP diagnosed at...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.