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Article

Carriage of mutations R462Q (rs 486907) and D541E (rs 627928) of the RNASEL gene and risk factors in patients with prostate cancer in Burkina Faso.

BMC medical genomics - 2 Jun 2022

Kadanga Essonan, Zouré Abdou Azaque, Zohoncon Théodora M, Traoré Lassina, Ky Bienvenu Désiré, Yonli Albert Théophane, Traoré Djé Djénèba Aïda, Bazié Bapio Valery Jean Télesphore Elvira, Sombié Herman Karim, Sorgho Pegdwendé Abel, Tovo Sessi Frida Appoline, Traoré Kalifou, Ouedraogo Teega-Wendé Clarisse, Djigma Florencia W, Simpore Jacques

Abstract excerpt

BACKGROUND: Prostate cancer (Pca) is a public health problem that affects men, usually of middle age or older. It is the second most common cancer diagnosed in men and the fifth leading cause of death. The RNASEL gene located in 1q25 and identified as a susceptibility gene to hereditary prostate cancer, has never been studied in relation to prostate cancer in Burkina Faso. The aim of this study was to analyze the...

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PMID: 35655265
DOI: 10.1186/s12920-022-01279-9
PMCID: PMC9161613

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