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Article

A New Human MR Splice Variant Is a Ligand-Independent Transactivator Modulating Corticosteroid Action

1 Sept 2001

Abstract excerpt

Aldosterone effects are mediated by the MR, which possesses the same affinity for mineralocorticoids and glucocorticoids. In addition to the existence of mechanisms regulating intracellular hormone availability, we searched for human MR splice variants involved in tissue-specific corticosteroid function. We have identified a new human MR isoform, hMRDelta5,6, resulting from an alternative splicing event skipping...

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Identifiers

PMID: 11518808
DOI: 10.1210/mend.15.9.0689

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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