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Article

Identification of a Novel Modulator of Thyroid Hormone Receptor-Mediated Action

20 Nov 2007

Abstract excerpt

BACKGROUND: Diabetes is characterized by reduced thyroid function and altered myogenesis after muscle injury. Here we identify a novel component of thyroid hormone action that is repressed in diabetic rat muscle. METHODOLOGY/PRINCIPAL FINDINGS: We have identified a gene, named DOR, abundantly expressed in insulin-sensitive tissues such as skeletal muscle and heart, whose expression is highly repressed in muscle...

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Share to Growth Hormone and Insulin-like Growth Factors
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PMID: 18030323
DOI: 10.1371/journal.pone.0001183

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