The Molecular Basis of Thyroid Hormone Action

doi:10.1056/nejm199409293311306

Article

The Molecular Basis of Thyroid Hormone Action

29 Sept 1994

Abstract excerpt

Progress has been made in understanding the molecular basis of a number of clinical manifestations of thyroid disease, yet many questions remain. Why are there two thyroid hormone-receptor genes? Is the function of each of the two receptors indeed unique? How T3 receptors interact with other nuclear proteins and DNA-binding sites and how these interactions are influenced by T3 is incompletely understood. The...

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