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Article

Genetic predisposition for a compromised immune system after multiple trauma.

Shock (Augusta, Ga.) - 1 Dec 2005

Hildebrand Frank, Pape Hans-Christoph, van Griensven Martijn, Meier Sven, Hasenkamp Sandra, Krettek Christian, Stuhrmann Manfred

Abstract excerpt

Severe trauma induces sustained changes of the immune response, which are thought to be related to secondary organ dysfunction. Despite a similar injury severity, the extent of the inflammatory response may vary between polytraumatized patients. It is unclear whether inflammatory variability is associated with genetic variations. In this prospective cohort study, patients were included when the following criteria...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Polymorphism, Restriction Fragment Length

Share to Polymorphism, Single Nucleotide

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Share to Systemic Inflammatory Response Syndrome

Source

Identifiers

PMID: 16317381
DOI: 10.1097/01.shk.0000184212.97488.4e

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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