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Article

Clinical associations of host genetic variations in the genes of cytokines in critically ill patients.

Clinical and experimental immunology - 1 Jun 2015

Belopolskaya O B, Smelaya T V, Moroz V V, Golubev A M, Salnikova L E

Abstract excerpt

Host genetic variations may influence a changing profile of biochemical markers and outcome in patients with trauma/injury. The objective of this study was to assess clinical associations of single nucleotide polymorphisms (SNPs) in the genes of cytokines in critically ill patients. A total of 430 patients were genotyped for SNPs in the genes of pro- (IL1B, IL6, IL8) and anti-inflammatory (IL4, IL10, IL13)...

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Identifiers

PMID: 25619315
DOI: 10.1111/cei.12592
PMCID: PMC4449781

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Source receipt: pubmed, retrieved 7 Sept 2026.

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