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Article

Association of IL-8-251A/T polymorphism with incidence of Acute Respiratory Distress Syndrome (ARDS) and IL-8 synthesis after multiple trauma.

Cytokine - 1 Mar 2007

Hildebrand Frank, Stuhrmann Manfred, van Griensven Martijn, Meier Sven, Hasenkamp Sandra, Krettek Christian, Pape Hans-Christoph

Abstract excerpt

INTRODUCTION: Interleukin-8 (IL-8) is regarded as one of the most important mediators in the pathogenesis of Adult Respiratory Distress Syndrome (ARDS). However, knowledge regarding the influence of genetic variations within the IL-8 gene either on the development of ARDS or on IL-8 production in the traumatic setting is sparse. PATIENTS AND METHODS: In this prospective cohort study, patients were included if the...

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PMID: 17498967
DOI: 10.1016/j.cyto.2007.03.008

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