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No association between the tryptophan hydroxylase gene polymorphism and major depressive disorders and antidepressant response in a Korean population.

Psychiatric genetics - 1 Dec 2005

Ham Byung-Joo, Lee Min-Soo, Lee Heon-Jeong, Kang Rhee-Hun, Han Chang-Su, Choi Myoung-Jin, Lee Seung-Hwan, Ryu Seung-Ho

Abstract excerpt

The serotonergic neurotransmitter system has been implicated in major depressive disorder (MDD) and appears to be the target of a variety of antidepressants. Tryptophan hydroxylase (TPH) is the rate-limiting enzyme in serotonin biosynthesis, and selective serotonin re-uptake inhibitors exert their activity enhancing the general serotonergic tone. The goal of this study was to investigate whether the A218C...

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Source

Identifiers

PMID: 16314762
DOI: 10.1097/00041444-200512000-00014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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No association between the tryptophan hydroxylase gene polymorphism and major depressive disorders and antidepressant response in a Korean population.PMID 16314762Read ↗

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