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Article

TPH1 218A/C polymorphism is associated with major depressive disorder and its treatment response.

Neuroscience letters - 1 Jan 2010

Viikki Merja, Kampman Olli, Illi Ari, Setälä-Soikkeli Eija, Anttila Sami, Huuhka Martti, Nuolivirta Timo, Poutanen Outi, Mononen Nina, Lehtimäki Terho, Leinonen Esa

Abstract excerpt

The association between the tryptophan hydroxylase 1 (TPH1) 218A/C polymorphism and (1) severity of major depressive disorder (MDD) and (2) response to treatment was studied. There were three study populations, the first consisting of 119 treatment-resistant MDD inpatients treated with electro-convulsive therapy (ECT), and the second of 98 MDD open care patients treated with selective serotonin reuptake...

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Source

Identifiers

PMID: 19874868
DOI: 10.1016/j.neulet.2009.10.069

Genes

TPH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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