Article
Inhibited neurogenesis in JNK1-deficient embryonic stem cells.
Molecular and cellular biology - 1 Dec 2005
Amura Claudia R, Marek Lindsay, Winn Robert A, Heasley Lynn E
Abstract excerpt
The JNKs are components of stress signaling pathways but also regulate morphogenesis and differentiation. Previously, we invoked a role for the JNKs in nerve growth factor (NGF)-stimulated PC12 cell neural differentiation (L. Marek et al., J. Cell. Physiol. 201:459-469, 2004; E. Zentrich et al., J. Biol. Chem. 277:4110-4118, 2002). Herein, the role for JNKs in neural differentiation and transcriptional regulation...
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