A Subtractive Gene Expression Screen Suggests a Role of Transcription Factor AP-2α in Control of Proliferation and Differentiation

Abstract excerpt

The transcription factor AP-2 alpha has been implicated as a cell type-specific regulator of gene expression during vertebrate embryogenesis based on its expression pattern in neural crest cells, ectoderm, and the nervous system in mouse and frog embryos. AP-2 alpha is prominently expressed in cranial neural crest cells, a population of cells that migrate from the lateral margins of the brain plate during closure...

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