Article
Promoter analysis in ES cell-derived neural cells.
Biochemical and biophysical research communications - 4 Feb 2005
Xian Hai-Qing, Werth Kelly, Gottlieb David I
Abstract excerpt
Neural cells derived from ES cells in cell culture (ESNCs) have many of the properties of normal neural cells and provide a model of "neurogenesis-in-a-dish." Here we show that ESNCs provide a powerful system for analyzing neural gene transcription. ES cells are transfected with bacterial artificial chromosomes (BACs) containing Olig2, a gene with a key role in neural fate choice. One BAC is modified by...
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