Article
C-Jun terminal kinases play an important role in regulating embryonic survival and eye development in vertebrates.
Current molecular medicine - 1 Jan 2013
Huang X-Q, Huang Z-X, Li Z-L, Chen X-W, Li X, Tang X-C, Liu F-Y, Liu Y, Chen L, Han W-J, Liu L, Li L, Wu K-L, Wu M-X, Liu X-L, Luo L-X, Yu M-B, Liu Y-Z, Liu S-J, Li D W-C
Abstract excerpt
The c-Jun N-terminal kinases (JNKs) constitute one of the three major types of mitogen-activated protein kinases. Previous studies showed that JNK mediates multiple signaling transduction pathways implicated in cell proliferation, differentiation, inflammation, stress response and apoptosis in mammals. In the present study, we use goldfish as a model system and demonstrate that JNK kinases are necessary to...
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