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Article

Interacting residues in an activated state of a G protein-coupled receptor.

The Journal of biological chemistry - 27 Jan 2006

Lee Yong-Hun, Naider Fred, Becker Jeffrey M

Abstract excerpt

Ste2p, the G protein-coupled receptor (GPCR) for the tridecapeptide pheromone alpha-factor of Saccharomyces cerevisiae, was used as a model GPCR to investigate the role of specific residues in the resting and activated states of the receptor. Using a series of biological and biochemical analyses of wild-type and site-directed mutant receptors, we identified Asn(205) as a potential interacting partner with the...

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PMID: 16314417
DOI: 10.1074/jbc.M509987200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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