Article
Functional and physical interactions among Saccharomyces cerevisiae α-factor receptors.
Eukaryotic cell - 1 Oct 2012
Gehret Austin U, Connelly Sara M, Dumont Mark E
Abstract excerpt
The α-factor receptor Ste2p is a G protein-coupled receptor (GPCR) expressed on the surface of MATa haploid cells of the yeast Saccharomyces cerevisiae. Binding of α-factor to Ste2p results in activation of a heterotrimeric G protein and of the pheromone response pathway. Functional interactions between α-factor receptors, such as dominant-negative effects and recessive behavior of constitutive and hypersensitive...
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