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Article

The PSEA promoter element of the Drosophila U1 snRNA gene is sufficient to bring DmSNAPc into contact with 20 base pairs of downstream DNA.

Nucleic acids research - 1 Jan 2005

Lai Hsien-Tsung, Chen Hsiang, Li Cheng, McNamara-Schroeder Kathleen J, Stumph William E

Abstract excerpt

Most of the major spliceosomal small nuclear RNAs (snRNAs) (i.e. U1, U2, U4 and U5) are synthesized by RNA polymerase II (pol II). In Drosophila melanogaster, the 5'-flanking DNA of these genes contains two conserved elements: the proximal sequence element A (PSEA) and the proximal sequence element B (PSEB). The PSEA is essential for transcription and is recognized by DmSNAPc, a multi-subunit protein complex....

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PMID: 16314318
DOI: 10.1093/nar/gki972
PMCID: PMC1292993

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The PSEA promoter element of the Drosophila U1 snRNA gene is sufficient to bring DmSNAPc into contact with 20 base pairs of downstream DNA.PMID 16314318Read ↗

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