Article
Protein-RNA interactions in the U5 snRNP of Saccharomyces cerevisiae.
RNA (New York, N.Y.) - 1 Oct 1998
Dix I, Russell C S, O'Keefe R T, Newman A J, Beggs J D
Abstract excerpt
We present here the first insights into the organization of proteins on the RNA in the U5 snRNP of Saccharomyces cerevisiae. Photo-crosslinking with uniformly labeled U5 RNA in snRNPs reconstituted in vitro revealed five contacting proteins, Prp8p, Snu114p, p30, p16, and p10, contact by the three smaller proteins requiring an intact Sm site. Site-specific crosslinking showed that Snu114p contacts the 5' side of...
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