Article
Novel polymorphisms at codons 146 and 151 in the prion protein gene of Cyprus goats, and their association with natural scrapie.
Veterinary journal (London, England : 1997) - 1 Mar 2007
Papasavva-Stylianou Penelope, Kleanthous Marina, Toumazos Pavlos, Mavrikiou Petroula, Loucaides Phedias
Abstract excerpt
To discern whether an association exists between specific combinations of polymorphisms of the prion protein (PrP) and natural scrapie in Cyprus goats, 250 goats were examined, including 164 histologically positive cases. Previously reported amino acid polymorphisms were detected at codons 154 (R-->H), 168(P-->Q), 220(Q-->H) and 240 (S-->P) and nucleotide alterations at codons 42 (a-->g) and 138 (c-->t)....
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